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EncyclopediaSeetoxic epidermal necrolysisLyell syndrome
tox·ic ep·i·der·mal ne·crol·y·sis (TEN), a syndrome in which a large portion of the skin becomes intensely erythematous with epidermal necrosis and peels off in the manner of a second-degree burn, often simultaneous with the formation of flaccid bullae, resulting from drug sensitivity or of unknown cause; the level of separation is subepidermal, unlike staphylococcal scalded skin syndrome in which there is subcorneal change. Synonym(s): Lyell syndromeLyell syndrome Erythema multiforme, see there. tox·ic ep·i·der·mal ne·crol·y·sis (TEN) (tok'sik ep'i-dĕr'măl nĕ-krol'i-sis) A syndrome in which a large portion of the skin becomes intensely erythematous, with epidermal necrosis and flaccid bullae, resulting from drug sensitivity or of unknown cause.
Synonym(s): Lyell syndrome. Lyell, Alan, 20th century Scottish dermatologist. Lyell disease - a disease affecting infants in which large areas of skin peel off as a result of upper respiratory staphylococcal infection. Synonym(s): Ritter disease; Ritter syndrome; staphylococcal scalded skin syndromeLyell syndrome - a syndrome in which a large portion of the skin becomes intensely erythematous with epidermal necrosis, and peels off. Synonym(s): toxic epidermal necrolysis |