tooth agenesis, selective, type 1
tooth agenesis, selective, type 1
A condition (OMIM:106600) characterised by non-syndromic agenesis of one or more teeth, which is divided into hypodontia (agenesis of less than 6 permanent teeth) and oligodontia (agenesis of 6 or more permanent teeth).Molecular pathology
Caused by defects of MSX1, which encodes a homeobox protein involved in epithelial-mesenchymal signalling that has roles in craniofacial development.