| 释义 |
EncyclopediaSeeschiffliSchilder disease
Schil·der dis·ease (shil'der), term used to describe at least two separate disorders described by Schilder: 1) Diffuse sclerosis or encephalitis periaxialis diffusa; a nonfamilial disorder affecting primarily children and young adults and characterized by progressive dementia, visual disturbances, deafness, pseudobulbar palsy, and hemiplegia or quadriplegia. Most patients die within a few years of onset; pathologically, there is a large, asymmetric area of myelin destruction, sometimes involving an entire cerebral hemisphere, and typically with extension across the corpus callosum. 2) The leukodystrophies. Synonym(s): encephalitis periaxialis diffusaSchil·der dis·ease (shil'dĕr di-zēz') Term used to describe at least two separate disorders described by Schilder: 1) diffuse sclerosis or encephalitis periaxialis diffusa; a nonfamilial disorder affecting primarily children and young adults and characterized by progressive dementia, visual disturbances, deafness, pseudobulbar palsy, and hemiplegia or quadriplegia. Most patients die within a few years of onset; pathologically, there is a large, asymmetric area of myelin destruction, sometimes involving an entire cerebral hemisphere, and typically with extension across the corpus callosum. 2) the leukodystrophies.
Synonym(s): encephalitis periaxialis diffusa. Schilder diseaseS02-838240 (shil'der) [Paul Ferdinand Schilder, Austrian-U.S. neurologist, 1886–1940] A rare demyelinating disease of the central nervous system (a variant of multiple sclerosis). It results in brain lesions that may resemble tumors or abscesses during neuroimaging. The disease may respond to treatment with immunosuppressing drugs. Synonym: myelinoclastic diffuse sclerosisSchilder, Paul Ferdinand, Austrian neurologist, 1886-1940. Addison-Schilder disease - Synonym(s): Schilder diseaseFlatau-Schilder disease - Synonym(s): Schilder diseaseSchilder disease - encephalitis periaxialis diffusa; progressive demyelinating disorder in adults; early symptom is visual impairment with mental deterioration. Synonym(s): Addison-Schilder disease; Flatau-Schilder disease; Schilder syndromeSchilder encephalitisSchilder syndrome - Synonym(s): Schilder disease |