crystal-storing histiocytosis

crystal-storing histiocytosis

A rare complication of low-grade B cell lymphoma and monoclonal gammopathies, including myelomas, which is characterised by lysosomal storage of kappa light chain (KLC) crystals.
Clinical findings
It may be associated with adult Fanconi syndrome, chronic tubulo-interstitial nephritis with accumulation of monoclonal KLC crystals within proximal tubular cell.
DiffDx
Benign rhabdomyoma.