| 释义 |
sitosterol Biochem.|saɪˈtɒstərɒl|
[ad. G. sitosterin (R. Burián 1897, in Sitzungsber. der K. Akad. der Wissensch. (Math.-Nat. Classe) CVI. iib. 549), f. Gr. σῖτο-ς grain, bread + G. -sterin after phytosterin (see phyto-); cf. phytosterol, -sterol.]
Any of a number of closely similar crystalline sterols, most of them isomers of formula C29H50O, first isolated from corn oil and widely distributed in plants; spec. the most common such substance, β-sitosterol, also called cinchol.
Before 1926 considered to be a single substance.
1898Jrnl. Chem. Soc. LXXIV. i. 72 A substance..is obtained which resembles the cholesterol of bile in external appearance and in composition..; it is named sitosterol. 1926Jrnl. Amer. Chem. Soc. XLVIII. 2986 The substance corresponding in composition to sitosterol..is not homogeneous. It is a mixture containing at least three isomeric sterols... It is proposed to name these isomers α-, β- and γ-sitosterol. 1943Ann. Reg. 1942 358 Work on algal chemistry showed that sitosterol, the characteristic sterol of the phanerogams, is common to the green algæ. 1962J. H. Burn Drugs, Med. & Man v. 57 The substance sitosterol can be given which prevents the cholesterol which is in the diet from being absorbed through the wall of the intestine. 1974M. C. Gerald Pharmacol. xxii. 401 Sitosterols enhance the elimination of cholesterol in the feces. |