单词 | abiotrophy |
释义 | abiotrophyn. Now chiefly Veterinary Medicine. Premature degeneration of cells or tissue (now usually within the central nervous system), esp. when hereditary or otherwise independent of external factors; an instance of this; any condition characterized by this. ΘΚΠ the world > health and disease > ill health > a disease > diseases of tissue > wasting disease > [noun] wasting1398 pininga1450 consumation1551 waste1570 marasmus1574 colliquation1601 marasme1612 decrement1646 wearing1654 unnourishment1662 decline1783 undermining1897 abiotrophy1902 1902 W. R. Gowers in Lancet 12 Apr. 1003/1 Here the simplest mode of obtaining what we need is to insert the root of βιος after the negative particle in ‘atrophy’ which gives us ‘abiotrophy’. But it is generally better, if you can, to appropriate what you need than to make it afresh, and we find the word βιοτροϕος used in the sense of ‘vital nutrition’. If we prefix the negative particle we have the same word, ‘abiotrophy’. 1915 Lancet 15 Oct. 986/1 None of the investigators who have recorded instances of this curious association of cataract and myopathy have ventured on any hypothesis as to its significance, except in so far as each condition has been regarded as the expression of a localised abiotrophy. 1938 J. H. Parsons Dis. Eye (ed. 9) xvii. 343 Treacher Collins, however, has advanced the theory that the disease is due to abiotrophy of the neuro-epithelium. 1949 H. W. C. Vines Green's Man. Pathol. (ed. 17) xxxviii. 1100 Primary neuronal degeneration.—It has been suggested for want of better explanation that the diseases of this group are due to ‘abiotrophy,’ a term indicating an inherent defect in the materials used for the construction of the nerve-tissues, so that about the time of middle life they are unable to survive the strain and undergo senility and decay. 1979 Adv. Human Genetics 9 ii. 93 The term abiotrophy is usually reserved for an apparently nonmetabolic disturbance of function in an organ previously apparently normally developed and functioning. 1986 Austral. Vet. Jrnl. 63 18 This previously unreported disorder may be an hereditary cerebellar abiotrophy of Merino sheep. 1999 D. Rice Chesapeake Bay Retrievers 87/2 Other hereditary diseases that are reported to occur in the Chessie are cerebellar abiotrophy, overbite, and underbite. 2007 Weekly Times (Austral.) (Nexis) 8 Aug. 9 Up to 90 per cent of kelpie dogs in Australia may have carriers of Cerebellar Abiotrophy (CA) in their pedigree. Derivatives ˌabioˈtrophic adj. ΘΚΠ the world > health and disease > ill health > a disease > diseases of tissue > wasting disease > [adjective] pinedOE dwined?a1366 tabefactc1425 consumptive1648 languishing1683 dwining1718 marasmoid1857 marasmous1857 marasmic1876 marantic1881 abiotrophic1902 1902 W. R. Gowers in Lancet 12 Apr. 1007/2 I would especially impress upon you the fact which is illustrated by the lad whom I have shown you—the sporadic occurrence of these abiotrophic diseases. 1962 A. Sorsby in A. Pirie Lens Metabolism 297 The distinction between congenital and abiotrophic defect is not readily applied to cataract. 1991 Cosmetics & Toiletries Mar. 74/1 Microcirculatory activation is indicated..for the management of the aging skin..and of the regressive abiotrophic pannicular disease of the lower limbs and the female breast secondary to venous stasis and/or chronic venous insufficiency. 2006 Jrnl. Feline Med. & Surg. 8 424 Some degenerative conditions..are considered examples of abiotrophic diseases. This entry has been updated (OED Third Edition, September 2009; most recently modified version published online December 2021). < n.1902 |
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