nortriptylinen.

Brit.

/nɔːrˈtrɪptᵻliːn/, U.S.

/nɔrˈtrɪptəˌlin/

Origin: Formed within English, by derivation. Etymons: nor- prefix, tri- comb. form, heptyl n. at heptane n. Derivatives, -ine suffix⁵.

Etymology: < nor- prefix + tri- comb. form + -ptyl (in heptyl n. at heptane n. Derivatives) + -ine suffix⁵. Compare slightly earlier amitriptyline n. and slightly later protriptyline n.

Pharmacology.

A tricyclic antidepressant drug, C₁₉H₂₁N, with actions and uses similar to those of amitriptyline, and given orally as the hydrochloride.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs

Marsilid1952

iproniazid1953

levallorphan1953

imipramine1958

Tofranil1958

isocarboxazid1959

Marplan1959

Nardil1959

nialamide1959

Niamid1959

phenelzine1959

tranylcypromine1959

Parnate1960

amitriptyline1961

monoamine oxidase inhibitor1962

nortriptyline1962

protriptyline1963

MAOI1965

maprotiline1970

mianserin1970

amoxapine1971

fluoxetine1975

paroxetine1977

Prozac1985

Seroxat1985

1962 Jrnl. Nerv. & Mental Dis. 134 564/1 Nortriptyline..is 5-(gamma-methylaminopropylidene) dibenzo[a,d]cyclohepta[1,4]diene hydrochloride.

1978 Nature 23 Mar. 330/1 The tricyclic anti~depressant drugs which are tertiary amines..were more potent inhibitors than those which are secondary amines (desmethylimipramine, nortriptyline, protriptyline).

1991 Pulse 6 Apr. 74/1 Nortriptyline may be tried in patients unable to tolerate amitriptyline.

2000 Esquire June 74 (advt.) Antidepressents such as nortriptyline, amitriptyline, imipramine, desipramine and fluoxetine.

This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022).

单词	nortriptyline
释义	nortriptylinen. Brit. /nɔːrˈtrɪptᵻliːn/, U.S. /nɔrˈtrɪptəˌlin/ Origin: Formed within English, by derivation. Etymons: nor- prefix, tri- comb. form, heptyl n. at heptane n. Derivatives, -ine suffix⁵. Etymology: < nor- prefix + tri- comb. form + -ptyl (in heptyl n. at heptane n. Derivatives) + -ine suffix⁵. Compare slightly earlier amitriptyline n. and slightly later protriptyline n. Pharmacology. A tricyclic antidepressant drug, C₁₉H₂₁N, with actions and uses similar to those of amitriptyline, and given orally as the hydrochloride. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > medicine for mental conditions > [noun] > antidepressant > specific drugs Marsilid1952 iproniazid1953 levallorphan1953 imipramine1958 Tofranil1958 isocarboxazid1959 Marplan1959 Nardil1959 nialamide1959 Niamid1959 phenelzine1959 tranylcypromine1959 Parnate1960 amitriptyline1961 monoamine oxidase inhibitor1962 nortriptyline1962 protriptyline1963 MAOI1965 maprotiline1970 mianserin1970 amoxapine1971 fluoxetine1975 paroxetine1977 Prozac1985 Seroxat1985 1962 Jrnl. Nerv. & Mental Dis. 134 564/1 Nortriptyline..is 5-(gamma-methylaminopropylidene) dibenzo[a,d]cyclohepta[1,4]diene hydrochloride. 1978 Nature 23 Mar. 330/1 The tricyclic anti~depressant drugs which are tertiary amines..were more potent inhibitors than those which are secondary amines (desmethylimipramine, nortriptyline, protriptyline). 1991 Pulse 6 Apr. 74/1 Nortriptyline may be tried in patients unable to tolerate amitriptyline. 2000 Esquire June 74 (advt.) Antidepressents such as nortriptyline, amitriptyline, imipramine, desipramine and fluoxetine. This entry has been updated (OED Third Edition, December 2003; most recently modified version published online March 2022). < n.1962
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