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单词 phenanthridine
释义

phenanthridinen.

Brit. /fᵻˈnanθrᵻdiːn/, /fɛˈnanθrᵻdiːn/, U.S. /fəˈnænθrəˌdin/, /fɛˈnænθrəˌdin/
Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: phenanthrene n., -idine suffix.
Etymology: < phenanthr- (in phenanthrene n.) + -idine suffix, after German Phenanthridin (A. Pictet 1886, in Berichte der Deutsch. Chem. Ges. 19 1063). Compare French méthylphénanthridine (M. A. Etard 1882, in Compt. rend. 95 732).
Chemistry.
A crystalline heteroaromatic compound, C13H9N, which has the tricyclic molecular structure of phenanthrene but with a nitrogen atom replacing one of the CH groups in the central ring. Also: any of various compounds containing this ring system, some of which have been used as trypanocidal drugs.
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the world > matter > chemistry > crystallography (general) > crystal (general) > [noun] > crystalline compound > specific
alcoholate1816
alcoate1828
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nitroanisidine1850
purpurein1864
quinizarin1873
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phenanthridine1890
the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [noun] > other internal parasiticides > specific drugs
phenanthridine1890
trypan red1905
trypan blue1911
tryparsamide1921
Bayer 2051922
stibophen1941
stilbamidine1941
suramin1941
mepacrine1943
PABA1943
metronidazole1960
stibocaptate1962
the world > health and disease > healing > medicines or physic > medicines for specific purpose > remedies for parasitic infections > [adjective] > destroying other internal parasites > specific drugs
phenanthridine1890
1890 Jrnl. Chem. Soc. 58 i. 390 Phenanthridine..was obtained by passing the vapour of benzylideneaniline..through an iron tube filled with pumice and heated to bright redness or nearly to whiteness.
1924 Chem. Age 25 Oct. 418/1 A few phenanthridines have been investigated but no products of interest as dyestuffs have so far been discovered.
1951 A. Grollman Pharmacol. & Therapeutics xx. 416 Trypanosomiasis in cattle has been effectively treated by certain phenanthridines.
1989 K. L. Yielding in P. E. Nielsen Photochemical Probes in Biochem. 241 These studies were designed to identify by photoaffinity labeling the putative action sites for phenanthridine and acridine drugs.
This entry has been updated (OED Third Edition, December 2005; most recently modified version published online March 2022).
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n.1890
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