Zenkern.1
/ˈzɛŋkə/, /ˈtsɛŋkə/, U.S. /ˈzɛŋkər/, /ˈtsɛŋkər/ 1. In the genitive, attributive, and with of, esp. in Zenker's degeneration. Designating a type of degeneration affecting skeletal and cardiac muscle, in which fibres lose their striations and appear uniformly eosinophilic.Such degeneration was originally described in cases of typhoid fever, but also occurs in other infectious diseases and as a result of nutritional deficiency, toxin ingestion, etc.
ΚΠ
1872 Trans. Clin. Soc. 1871–2 5 214 Here and there some of the fibres presented the advanced condition of the waxy degeneration of Zenker.
1898 W. S. Lazarus-Barlow Man. Gen. Pathol. xii. 521 In Zenker's degeneration the muscular fibres themselves look dull and semi-opaque, and microscopically are found to have lost their striation.
1900 Jrnl. Compar. Pathol. & Vet. Arch. 21 751 The degeneration of the psoas muscle is quite analogous to the Zenker degeneration seen in typhoid fever.
1966 G. P. Wright et al. Systemic Pathol. I. xvi. 525/1 Other findings in typhoid include..Zenker's degeneration of the abdominal muscles.
2016 Mitochondrion 30 36/2 Cases were further confirmed to suffer from AM [= atypical myopathy] on the basis of..histopathological findings showing a multifocal process compatible with Zenker's degeneration and necrosis in fibres of postural and/or respiratory muscles.
2. In the genitive and attributive. Designating a type of diverticulum occurring at the junction of the pharynx and the oesophagus (pharyngo-oesophageal diverticulum).This type of diverticulum has also been called pulsion diverticulum, although pressure within the oesophagus is probably only one factor in its development.
ΚΠ
1897 B. T. Tilton tr. H. Tillmanns Text-bk. Surg. II. 650 Zenker's pressure diverticula arise from pressure from within, which causes a bulging outward of the œsophageal wall.
1932 Jrnl. Amer. Med. Assoc. 98 965/2 The symptoms of a Zenker pulsion diverticulum depend on the size of the pouch.
1975 Year Bk. Ear, Nose & Throat 279 A variety of neuromuscular disorders, with or without Zenker's diverticulum.
2015 D. M. Yousem Head & Neck Imaging (ed. 4) 142 The Zenker diverticulum typically arises from the posterior wall.
This entry has been updated (OED Third Edition, June 2018; most recently modified version published online March 2022).
Zenkern.2
/ˈzɛŋkə/, /ˈtsɛŋkə/, U.S. /ˈzɛnkər/, /ˈtsɛŋkər/ Histology.
In the genitive and attributive. Designating a fixative containing mercury( ii) chloride and potasium dichromate, used to prepare samples for microscopy. Esp. in Zenker's fluid, Zenker's fixative.
ΚΠ
1894 Jrnl. Royal Microsc. Soc. 758 Zenker's Fixative.—Dr. K. Zenker recommends as a fixative the following solution.
1902 E. A. Schäfer Essent. Histol. (ed. 6) 397 General methods of preserving and hardening tissues and organs.—The fluids which are more commonly used are..Müller's fluid (bichromate of potash 2½ parts, sulphate of soda 1 part, water 100 parts); Zenker's fluid (which is Müller's fluid containing 5 parts per cent. of mercuric chloride, to which 5 c.c. of acetic acid is added at the time of use); [etc.].
1922 Brain 44 359 The walls were thoroughly fixed with Zenker's fluid until of a leathery consistency and the wound was closed.
1950 H. Kirby Materials & Methods Study Protozoa iii. 44/2 Fixation may be in Schaudinn fluid, sublimate, or Zenker fluid, all preferably without acetic acid.
1972 Jrnl. Neurol. Sci. 17 348 Brain specimens were fixed by immersion of slices in Zenker fixative.
2002 Jrnl. Mammalogy 83 490/2 Tissues from reproductive tracts intended for light microscopic examination were immersed for fixation in..Zenker's fluid.
This entry has been updated (OED Third Edition, June 2018; most recently modified version published online March 2022).
<
n.11872
n.21894