单词 | carcinoembryonic |
释义 | carcinoembryonicadj. Medicine and Biology. Designating an antigen originally identified in gastrointestinal tumours and fetal colonic tissue, and the group of cell membrane glycoproteins, structurally related to immunoglobulins, to which this antigen belongs. Also: = oncofetal adj. at onco- comb. form (now rare). ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > immunogen or antigen > [adjective] > types of antigen precipitinogenic1935 carcinoembryonic1965 xenoantigenic1973 1965 P. Gold & S. O. Freedman in Jrnl. Exper. Med. 122 475 The results of the present investigation support the possibility of a distinct relationship between the system-specific tumor antigens and certain embryonic tissue components of the human digestive system. These common antigenic constituents will henceforth be referred to as ‘carcinoembryonic’ antigens of the human digestive system. 1972 Nature 21 Jan. 137/2 Table 1 is an attempt to classify the different types of onco-foetal ‘antigens’ (OFAs). It seems necessary to coin this phrase because the more elegant description of carcino-embryonic antigen has been pre-empted to describe one class of these compounds. 1980 Biochem. Med. 23 336 α-Fetoprotein (AFP) is one of several carcinoembryonic proteins synthesized in large amounts by the fetus. 1985 Washington Post 16 July a6/6 Sugarbaker said the most important blood test to check will be the CEA, or carcinoembryonic antigen, a protein sometimes released into the blood by colon cancer cells. 1995 Proc. National Acad. Sci. U.S.A. 92 12095/1 We have identified a member of the pregnancy-specific glycoprotein (PSG) subgroup of the carcinoembryonic antigen gene family. 2005 M. Suri & I. D. Young Genetics for Pediatricians i. 2 Investigations [in ataxia-telangiectasia] show elevated levels of α-fetoprotein and carcinoembryonic antigen and reduced levels of immunoglobulin. This is a new entry (OED Third Edition, June 2008; most recently modified version published online December 2021). < adj.1965 |
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